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1.
NeuroQuantology ; 20(16):5319-5326, 2022.
Article in English | EMBASE | ID: covidwho-2206879

ABSTRACT

Objective: Coronavirus disease 2019 may be associated with a white spectrum of post recovery disease complications and health impairment. The objective of this study was to evaluate and assess the different perimeters of pulmonary Function Tests and late outcome of the disease after hospital discharge at 3 and 6 months among the patients admitted with swerve COVID Pneumonia. Method(s): Our analysis consisted of comparison of the FVC at 3 and 6 months after hospital discharge in order to evaluate the disease severity with time. Result(s): A total of 41 hospitalized patients had their Pulmonary Function Tests evaluated >70% of the patients had their FVC <80% at 3 months and >12% had their FVC <80% at 6 months. To study abnormality of spirometry in severe post COVID-19 patients who were discharge from ICU hospital and complete the follow up after one month 3, 6. CONCLUSION(S): In patients who developed moderate to severe pneumonia more than 70% had abnormal FVC at 3 months. These patients were to be identified and treated with optimal management and as a result only 12% of patients had long term impairment in FVC and long term sequel. Copyright © 2022, Anka Publishers. All rights reserved.

2.
Journal of Pharmaceutical Negative Results ; 13:5568-5597, 2022.
Article in English | EMBASE | ID: covidwho-2206746

ABSTRACT

The COVID-19 pandemic has seriously influenced all over the world and affectedthe health of people. In COVID-19 patients, physiological disorders develop like stress, anxiety, and insomnia. This study aimed to investigate sleep quality in COVID-19hospitalized patients of Muzaffarabad, Azad Jammu, and Kashmir. Pittsburg Sleep Quality Index (PSQI) was used to measure sleep quality. PSQI was a self-rated questionnaire scale that contained seven components generated by the combination of 19 individual items. The components included were subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, use of sleep medication and, daytime dysfunction. All components score from "0" to "3". The score "0" indicates no problem and the sum of the score 3 indicates severe difficulty. The seven components score was added to yield one global score. A score of 0 to 5 indicated no sleep disturbance and a score of more than 5 indicated sleep disturbance. The mean global score was 8.88+/-4.716 (Mean+/-SD). Current research revealed that 72.2% (n=73) ofpatients who had a global score of 5 or more than 5 had poor sleep quality and 27.8% (n=31) who had a score of less than 5 had good sleep quality (n=31) 13 male patients hada good quality of sleep and 36 male patients experienced a bad quality of sleep. In females, 18 female patients had a good quality of sleep and 37 female patients had a bad quality of sleep current study revealed that there was no association between gender and global PSQI, so sleep quality is independent of gender (chi2 =6.497, P =0.090, df = 3). Thisstudy also showed association between PSQI global score and age group. The 1st age group 15-32 year had a total of 48 patients. The study revealed that 54.16% (n=26) patients had bad sleep quality and 45.83% (n=22) patients had good sleep quality. The second age group from 33 to 55 years in which 76% (n=19) patients had bad sleep quality and 24% (n=06) patients had good sleep quality (r=0.342, P=0.001, df=6) showed that there is high relationship difference between increase group and sleep quality which showed that increase in age group, sleep quality become bad. The 3rd age group was over. Copyright © 2022 Authors. All rights reserved.

3.
Journal of Pharmaceutical Negative Results ; 13:2780-2788, 2022.
Article in English | EMBASE | ID: covidwho-2206733

ABSTRACT

Background: Despite its widespread usage, invasive positive pressure ventilation (IPPV) has a dismal track record in COVID-19 patients with SARDS. Currently, there is a paucity of evidence supporting the usefulness of noninvasive positive pressure ventilation (NIPPV) in the treatment of severe ARDS, as well as a significant risk of aerosol formation in patients with COVID-19 infection. Objective(s): This study aims to assess the efficacy and safety of NIPPV administration to COVID-19 patients. Method(s): The trial included 130 participants with moderate tosevere ARDS based to the Berlin criteria (PaO2/FiO2 ratio of 200mmHg, GCS > 13, respiratory breathing index (RBI) of 105, and no systemic issues). They were treated with NIPPV with awake proaning up to 12 hours per day at a hospital in Muzaffarabad. The addition of a heat and moisture exchanger (HME) and viral/bacterial filters to the expiratory limb of the ventilator circuit represented a minor improvement. Result(s): In an average of six days, the PaO2/FiO2 ratio indicates that the severity of ARDS has improved from moderate/severe to mild in 64 percent of patients. 36 percent of individuals who had a defined airway experienced IPPV or failure of NIV. During the study period, 1 % the of healthcare workers (HCW) were infected with COVID19. The delivery of NIPPV was associated with claustrophobia, nasal crusting, aspiration, and barotrauma (0.7 percent). Conclusion(s): In selected patients, NIV with awake proaning up to 12 hours per day can be employed to give respiratory support without the need for IPPV, hence eliminating the need for IPPV in those patients. However, larger-scale investigations are required to validate our findings. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

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